The vectorborne Zika virus joins avian influenza Ebola and yellow fever as recent public health crises threatening pandemicity.By a combination of stochastic modeling and economic geography this book proposes two key causes together explain the explosive spread of the worst of the vectorborne outbreaks.Ecosystems in which such pathogens are largely controlled by environmental stochasticity are being drastically streamlined by both agribusinessled deforestation and deficits in public health and environmental sanitation.Consequently a subset of infections that once burned out relatively quickly in local forests are now propagating across susceptible human populations whose vulnerability to infection is often exacerbated in structurally adjusted cities. The resulting outbreaks are characterized by greater global extent duration and momentum.As infectious diseases in an age of nation states and global health programs cannot as much of the present modeling literature presumes be described by interacting populations of host vector and pathogen alone a series of control theory models is also introduced here. These models useful to researchers and health officials alike explicitly address interactions between government ministries and the pathogens they aim to control.