This book explores answers to the fundamental questions driving the research, innovation and practices of the latest revolution in scientific, technological and economic development: how does data science transform existing science, technology, industry, economy, profession and education? How does one remain competitive in the data science field?What is responsible for shaping the mindset and skillset of data scientists? Data Science Thinkingpaints a comprehensive picture of data science as a new scientific paradigm from the scientific evolution perspective, as data science thinking from the scientific-thinking perspective, as a trans-disciplinary science from the disciplinary perspective, and as a new profession and economy from the business perspective.